I can't predict which games my wife will play.
Some folks would probably stop me right there: "You're wife plays games?!? Amazing!!!" Don't go too far, my friends - she's not what we'd call "a gamer".
For the most part, she'll keep half an eye on what I'm playing. Every once in a while she'll actively pay attention, like during segments of F.E.A.R. and BioShock . I've offered her the controls, but she always declines saying that she doesn't want to play.
I was recently playing Neverwinter Nights (for the first time - bought it on day 1, and it's collected dust ever since), and she would occasionally peek over as she normally does. After a few days of this, out of the blue, she asks, "Does this game have multiplayer?"
"It does," I respond. "I'll get things set up so we can play tomorrow."
I spent the next few hours attaching a computer to the main TV, installing NWN on the TV computer, installing NWN on a laptop, and making sure the area looked nice (no wires running everywhich way). Even bought a new cordless keyboard/mouse combo for "her" computer.
We played all the way through the game.
She was a fighter (barbarian, I think) and I was a druid. She got enjoyment from her character's one-hit kills and the ability to charge into rooms with guns blazing, so to speak. I played the role of part-time healer and navigator. There were (thankfully only) a few quests that rewarded her with a weapon or armor that was above her level - these items worked as carrots, driving her forward in the game.
It was fun playing with her, but she hasn't expressed any interest in other RPG games.
She has taken a shine to Viva Piñata , which I picked up for myself for $5 at a local discount store. In fact, she's played it far more than I have!
She's also had a go with Plants vs. Zombies . And finished it. Multiple times. While not multiplayer, we'd chat about strategies and favorite plants.
And she's also enjoying Demigod . We play 2v2 co-op against the computer a few nights a week. We're at a point where we'll consistently win against the Hard AI. (I know some Demigod players will scoff, saying that Nightmare is too easy. Keep in mind that we're chatting about my non-gamer wife.)
I guess I can't call her a "non-gamer" anymore. "Gamer" seems too aggressive, however. Wherever she falls in the spectrum, I hope to find more games that we can play together. Being an avid gamer myself, I think the odds are with me.